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Carmaphycin-17

CAT: 0931-T211949-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211949-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2143080-91-3
Target
Proteasome, Parasite
Related Pathways
Microbiology/Virology, Proteases/Proteasome, Ubiquitination
Bioactivity
Carmaphycin-17 (CP-17) is a selective proteasome inhibitor with an EC50 of 217 nM. It exhibits potent antimicrobial activity against Trichomonas vaginalis and can overcome resistance to Metronidazole. In mouse models of vaginal trichomoniasis, CP-17 significantly reduces parasite burden after topical treatment without any observed adverse effects. Additionally, Carmaphycin-17 is useful for researching sexually transmitted diseases like trichomoniasis.
Smiles
C([C@@H](C(N[C@H](C(=O)[C@@]1(C)CO1)CC2=CC=CC=C2)=O)NC([C@H](CC=3C=4C(NC3)=CC=CC4)NC(CCCCC)=O)=O)C=5C=6C(NC5)=CC=CC6
Molecular Formula
C40H45N5O5
Molecular Weight
675.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
HY-171956Carmaphycin-17
MBS393792-01Heptadecanoic-17,17,17-D3 Acid
138536-AFCytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17)
138536-AF-FITCCytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (FITC)
138536-AF-APCCytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (APC)
MBS6122211-01Cytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (HRP)
MBS6122207-01Cytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (AP)
138536-AF-PECytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (PE)
138536-AF-BiotinCytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (Biotin)
INB76074-0117:0-17:1-17:0 Tg

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