3′,5′-DiOA-dC

CAT: 0931-T211671-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T211671-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

STING

Related Pathways

Immunology/Inflammation

Bioactivity

3’,5’-DiOA-dC is a hydrophobic nucleotide lipid and acts as a ligand for the STING agonist c-di-GMP (CDG) . It can assemble with CDG to form stable cyclic dinucleotide nanoparticles through molecular recognition-driven supramolecular forces. This interaction reduces tumor weight and volume while increasing the levels of CD8 T cells, neutrophils, and NK cells in the tumor microenvironment. Additionally, 3’,5’-DiOA-dC enhances TNF-α and IFN-γ levels in a mouse melanoma model.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-172533	3′,5′-DiOA-dC
GTR19218435-01	DIOA
ALX-550-263-M005	R- (+) -DIOA
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TRC-D852190-100MG	S-(-)-DIOA
TRC-D852191-50MG	S-(-)-DIOA-D9
TRC-D852181-50MG	R-(+)-DIOA-D9
N-1069-5	5-Formyl-dC
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3′,5′-DiOA-dC

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