MrgprX2-IN-1

CAT: 0931-MF-0118736-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0118736-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2792202-91-4
Target
MRGPR
Related Pathways
GPCR/G Protein
Bioactivity
MrgprX2-IN-1 (Compound 2-10) is a selective antagonist of the Mas-related G protein-coupled receptor X2 (MRGPRX2) . It functions by inhibiting mast cell degranulation and the release of inflammatory mediators mediated by MRGPRX2, thereby blocking non-IgE-dependent immune responses. MrgprX2-IN-1 holds potential for research into pseudo-allergic reactions, chronic pruritus, and inflammatory diseases.
Smiles
N(C=1N2C(=NC(C(F)(F)F)=C2)C=CC1)[C@@H]3CC[C@H](NC(=O)C4=C5C(C=NN5)=CC=C4)CC3
Molecular Formula
C22H21F3N6O
Molecular Weight
442.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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