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MrgprX2-IN-2

CAT: 0013-GTR19264314-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264314-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MrgprX2-IN-2 (Compound example 12) is a selective antagonist of the Mas-related G protein-coupled receptor X2 (MRGPRX2) . It works by inhibiting MRGPRX2-mediated mast cell degranulation and the release of inflammatory mediators, thus blocking non-IgE-dependent immune responses. MrgprX2-IN-2 shows potential for research in the areas of pseudo-allergic reactions, chronic pruritus, and inflammatory diseases.
CAS Number
2792205-87-7
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
N (C=1N2C (=NC (C (F) (F) F) =C2) C=CC1) [C@H]3CC[C@@H] (NC (=O) C4=CN (CC (F) (F) F) N=C4Cl) CC3
Molecular Formula
C20H19ClF6N6O
Molecular Weight
508.85
Storage Conditions
-20°C
Notes
For research use only.

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