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SGC0946 TFA

CAT: 0931-T211545-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211545-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
SGC0946 TFA is a selective inhibitor of DOT1L with an IC50 value of 0.3 nM. It induces G1 phase arrest in cancer cells by inhibiting DOT1L and reduces cellular self-renewal and metastatic potential while promoting cell differentiation. SGC0946 TFA is applicable in research for tumors such as leukemia and breast cancer and serves as a probe for studying the cellular mechanisms of DOT1L in both normal and diseased cells.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-15650-01SGC0946
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GTR19263915-01SGC0946 TFA
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