YZ-35

CAT: 0931-T211347-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T211347-01Size:10 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Target
Apoptosis|||STAT
Related Pathways
Apoptosis|||JAK/STAT signaling|||Stem Cells
Bioactivity
YZ-35 is a STAT3 inhibitor with a Ki value of 0.38 ?M. It binds directly to STAT3 with high affinity, having a dissociation constant (Kd) of 190 nM. YZ-35 effectively inhibits the dual phosphorylation of STAT3 at Tyr705 and Ser727 sites. It also suppresses colony formation, cell migration, and induces apoptosis in breast cancer cell lines. Additionally, YZ-35 selectively inhibits the self-renewal capability of breast cancer stem cells (BCSC) and reduces tumor growth in breast cancer stem cell xenograft models. YZ-35 is applicable for breast cancer research.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
T202216-01YZ-202
T203747-01YZ-268
T14326-01AS-35
T70484-01AD-35
T78783-01HBV-IN-35
T79554-01AChE-IN-35
T86624-01HSD17B13-IN-35
T63406-01HCV-IN-35
T62779-01PI3K-IN-35
T200078-01Tyrosinase-IN-35

Alternative Products

CatalogName
HY-175253YZ-35
sc-100438STK33 (YZ-16)
sc-100563MTHFS (YZ-M)
sc-101019RCK (YZ-14)
sc-101153Smad2 (YZ-13)
sc-73931ENA-78 (YZ-14)
sc-80213MT-MMP-2 (YZ-12)
40-0001-13GL RAPD Decamer 13-YZ Set
sc-534534Smad2 (YZ-13) : m-IgGκ BP-HRP Bundle
sc-547972Smad2 (YZ-13) : m-IgG2a BP-HRP Bundle

Popular Products