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HSD17B13-IN-35

CAT: 0931-T86624-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86624-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2770246-69-8
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-35 (compound 76) is a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of less than 0.1 μM using estradiol as the substrate. This compound is significantly relevant in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=NN(C=C4)C5=C(F)C=CC=C5)C3=O)=CC=C2
Molecular Formula
C25H16Cl2FN5O3
Molecular Weight
524.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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