PI3K-IN-35

• Target:

  Others|||PI3K|||Apoptosis

• Related Pathways:

  Apoptosis|||PI3K/Akt/mTOR signaling|||Others

• Bioactivity:

  PI3K-IN-35 (Compound 6l) is a highly selective inhibitor of PI3K, targeting PI3K-? (IC50: 13.98 ?M), PI3K-? (IC50: 7.22 ?M), and PI3K-? (IC50: 10.94 ?M) . It blocks the cell cycle in the G2/M phase and induces apoptosis, making it useful for studying leukemia.

• Smiles:

  C(#N)C=1C(=NC(NN=CC=2C=3C(NC2)=CC=CC3)=NC1N4CCOCC4)C5=CC=C(OC)C=C5

• Molecular Formula:

  C25H23N7O2

• Molecular Weight:

  453.5

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2458163-99-8