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PROTAC PDE4 degrader-1

CAT: 0931-T211269-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211269-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Interleukin, PDE, PROTACs, TNF
Related Pathways
PROTAC, Metabolism, Apoptosis, Immunology/Inflammation
Bioactivity
PROTACPDE4 degrader-1 (Compound 9m) is an orally active, selective PDEC4 PROTAC degrader with a DC50 of 41.98 μM. It effectively inhibits the secretion of pro-inflammatory cytokines, such as TNF-α and IL-6, and significantly reduces pulmonary inflammation in a mouse model of LPS-induced acute lung injury (ALI) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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