GT-02216

• CAS Number :

  2648407-76-3

• Target :

  Glycosidase

• Related Pathways :

  Metabolism

• Bioactivity :

  GT-02216 is capable of binding allosterically to GCase, thereby enhancing its function. In primary human fibroblasts, it increases GCase activity and decreases Tau accumulation in mutant GBA1 fibroblasts. Additionally, GT-02216 offers protection to hippocampal primary neurons exposed to Tau oligomer in a rat model.

• Smiles :

  O=C(C1=NC(N)=CC(=C1)NC=2C=CC=CC2O)N3CCN(C=4C=CC=CC4)CC3

• Molecular Formula :

  C22H23N5O2

• Molecular Weight :

  389.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C