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GT-0198 HCl

CAT: 0931-T70643-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T70643-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1440950-06-0
Target
Others
Related Pathways
Others
Bioactivity
GT-0198 is a novel glycine transporter 2 inhibitor showed activity in a mouse model of neuropathic pain. GT-0198 inhibited the function of glycine transporter 2 (GlyT2) in human GlyT2-expressing HEK293 cells and did not bind various major transporters or receptors of neurotransmitters in a competitive manner. GT-0198 is considered to be a comparatively selective GlyT2 inhibitor. GT-0198 is a structurally novel GlyT2 inhibitor bearing a phenoxymethylbenzamide moiety with in vivo efficacy in behavioral models of neuropathic pain.
Smiles
Cl.CN1CCC(CC1)NC(=O)c1ccc(COc2ccc(cc2)C(F)(F)F)cc1
Molecular Formula
C21H24ClF3N2O2
Molecular Weight
428.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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