IQM-266

CAT: 0931-T210509-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T210509-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1956337-58-8
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9986
Bioactivity
IQM-266 is a DREAM ligand (KD = 4.63 ?M) and KV4 current modulator. IQM-266 inhibits KV4.3/DREAM currents in a concentration-, voltage-, and time-dependent manner, increases transmembrane charge, and modulates IA currents in rat DRG neurons, making it a potential therapeutic candidate for neurological disorders.
Smiles
O=C(O)C1=CC=2C=CC=CC2C=C1NC(=O)CC=3C=CC=C(OC=4C=CC=CC4)C3
Molecular Formula
C25H19NO4
Molecular Weight
397.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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