Bcl-2-IN-20

CAT: 0931-T210259-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T210259-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Apoptosis, Bcl-2 Family, Reactive Oxygen Species

Related Pathways

Metabolism, NF-κB, Apoptosis, Immunology/Inflammation

Bioactivity

Bcl-2-IN-20 (Compound 81) is a Bcl-2 inhibitor with an IC50 of less than 10 μM, achieving a 79.1% inhibition rate at 9 μM. It demonstrates cytotoxicity in cell lines such as SK-MEL-28 (IC50 > 10 μM), A549 (IC50 = 6.1 μM), HepG2 (IC50 > 10 μM), MCF-7 (IC50 = 8.9 μM), HCT116 (IC50 > 10 μM), and HEK-293 (IC50 = 14.1 μM) . Bcl-2-IN-20 also promotes the generation of ROS, inducing apoptosis and DNA damage.

Molecular Formula

C22H14BrNO6S

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
GTR19262818-01	Bcl-2-IN-20
221022-01	Bcl-2 (Apoptosis Regulator Bcl-2, Bcl 2, BCL2) discontinued
MA1004	Bcl-2

Bcl-2-IN-20

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