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Bcl-2-IN-7

CAT: 0931-T63521-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63521-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Caspase, Apoptosis, Bcl-2 Family, MDM-2/p53, Others
Related Pathways
Others, Proteases/Proteasome, Apoptosis
Bioactivity
Bcl-2-IN-7 is a potent inhibitor of Bcl-2 (b-cell lymphoma-2), which can downregulate the expression of Bcl-2, increase the expression of p53, Bax, caspase-7 mRNA, and induce cell cycle arrest and apoptosis in MCF-7 cells of breast cancer. Bcl2-IN-7 showed good antitumor activity against MCF-7 cells (IC50: 20.17 μM), LoVo cells (IC50: 22.64 μM), HepG2 cells (IC50: 45.57 μM) and A549 cells (IC50: 51.50 μM) .
Molecular Formula
C24H22N4O5S2
Molecular Weight
510.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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sc-130308Bcl-2 (7)
GTR19185126-01Bcl-2-IN-7
GTR17962816Bcl-7 Antibody
307633-01BAK (Apoptosis regulator BAK, Bcl-2-like protein 7, CDN1, Bcl-2 homologous antagonist/killer, Apoptosis regulator BAK, Bcl-2-like protein 7, Bcl2-L-7)
221022-01Bcl-2 (Apoptosis Regulator Bcl-2, Bcl 2, BCL2) discontinued
MA1004Bcl-2
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