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Bcl-2-IN-20

CAT: 0013-GTR19262818-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262818-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bcl-2-IN-20 (Compound 81) is a Bcl-2 inhibitor with an IC50 of less than 10 μM, achieving a 79.1% inhibition rate at 9 μM. It demonstrates cytotoxicity in cell lines such as SK-MEL-28 (IC50 > 10 μM), A549 (IC50 = 6.1 μM), HepG2 (IC50 > 10 μM), MCF-7 (IC50 = 8.9 μM), HCT116 (IC50 > 10 μM), and HEK-293 (IC50 = 14.1 μM) . Bcl-2-IN-20 also promotes the generation of ROS, inducing apoptosis and DNA damage.
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Molecular Formula
C22H14BrNO6S
Storage Conditions
-20°C
Notes
For research use only.

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