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PI3Kδ-IN-22

CAT: 0931-T210218-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210218-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PI3K
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
PI3Kδ-IN-22 (Compound 26) is a selective inhibitor of PI3Kδ with a pKi value of 9.3. It effectively inhibits the PI3Kδ-AKT signaling pathway in THP-1 cells, demonstrating a pIC50 of 9.4. Additionally, PI3Kδ-IN-22 exhibits favorable pharmacokinetic properties in rats.
Molecular Formula
C27H35FN8O4S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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