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PI3Kα-IN-22

CAT: 0013-GTR19234772-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234772-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PI3Kα-IN-22 (Compound 17) is a potent, selective, and orally bioavailable inhibitor specifically targeting the oncogenic PI3Kα H1047R mutant. With an IC50 of 1 nM in cellular assays, it has shown promising antitumor efficacy, including tumor regression in the HCC1954 xenograft model, supporting its use in cancer research.
CAS Number
2925030-26-6
Field of Research
Signal Transduction
Smiles
[C@@H] (NC1=C (C (O) =O) C=CC=C1) (C) C=2C=3N (C (=O) C (C#N) =C (N3) N4CCC (F) (F) CC4) C=C (C) C2
Molecular Formula
C24H23F2N5O3
Molecular Weight
467.47
Storage Conditions
-20°C
Notes
For research use only.

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