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KOR agonist 2

CAT: 0931-T210176-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210176-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Opioid Receptor
Related Pathways
GPCR/G Protein, Endocrinology/Hormones, Neuroscience
Bioactivity
KOR agonist 2 (Compound 23p) is an agonist of the κ opioid receptor (κopioid receptor, KOR) with a Ki of 1.9 nM. In murine models, KOR agonist 2 demonstrates analgesic effects with an ED50 of 1.30 mg/kg. It exhibits high clearance in mice when administered intravenously at 2 mg/kg and shows high metabolism and clearance in liver microsomes.
Molecular Formula
C29H35ClN2O4S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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