KOR agonist 3

CAT: 0931-T203358-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T203358-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Opioid Receptor

Related Pathways

Neuroscience, Endocrinology/Hormones, GPCR/G Protein

Bioactivity

KOR agonist 3 (Compound 5) is an agonist of the κ opioid receptor (κOR) with an EC50 of 0.88 nM. It also exhibits some activation of μOR, with an EC50 of 720 nM. However, KOR agonist 3 does not activate δOR at concentrations below 1 μM. Its ability to recruit β-Arrestin-2 is lower than that of U50488.

Molecular Formula

C24H24N2O3

Molecular Weight

388.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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KOR agonist 3

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