KOR agonist 4

• Target:

  Opioid Receptor

• Related Pathways:

  GPCR/G Protein|||Neuroscience|||Endocrinology/Hormones

• Bioactivity:

  KOR agonist 4 (compound 39) is an agonist targeting the ? opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTP?S. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the ? opioid receptor over the ? (MOR) and ? (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.

• Molecular Formula:

  C21H25N3

• Molecular Weight:

  319.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C