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Nav1.7-IN-13

CAT: 0931-T209439-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209439-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2776235-57-3
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Nav1.7-IN-13 (compound 3g) is a sodium channel inhibitor that notably suppresses Veratridine-induced neuronal activity. It inhibits the total Na+ current in DRG neurons in a concentration-dependent manner and delays the activation of Navs. Nav1.7-IN-13 significantly alleviates mechanical pain behavior in a rat model of nerve injury (SNI), exhibiting analgesic properties.
Smiles
C(OC)(=O)[C@@]1(CC=2C(O1)=CC=CC2)[C@@]3(O)C=4C(N(CC=C(C)C)C3=O)=CC(Br)=CC4
Molecular Formula
C23H22BrNO5
Molecular Weight
472.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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