PRMT5-IN-33

CAT:
931-T209135-01
Size:
10 mg
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
PRMT5-IN-33 - image 1

PRMT5-IN-33

  • Target:

    Apoptosis|||Histone Methyltransferase
  • Related Pathways:

    Apoptosis|||Chromatin/Epigenetic
  • Bioactivity:

    PRMT5-IN-33 (compound A8) is a selective inhibitor of PRMT5 that competes with SAM, exhibiting an IC50 of 10.9 nM. It induces apoptosis and inhibits the proliferation of Z-138 and MOLM-13 cells, demonstrating antitumor activity.
  • Molecular Formula:

    C25H24BrN5O3S
  • Shipping Conditions:

    Cool pack
  • Storage Temperature:

    -20°C