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HDAC6-IN-31

CAT: 0931-T209038-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209038-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
HDAC
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
HDAC6-IN-31 (compound 8m) is a selective HDAC6 inhibitor with an IC50 of 0.026 μM. It significantly suppresses the production and release of pro-inflammatory cytokines. HDAC6 plays a crucial role in inhibiting inflammasome activation and holds potential for treating NLRP3 inflammasome-driven inflammatory diseases. Additionally, HDAC6-IN-31 inhibits the migration of glioblastoma cells.
Molecular Formula
C15H13FN4O2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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