AChE-IN-51

• Target:

  MMP|||Beta Amyloid|||Cholinesterase (ChE)

• Related Pathways:

  Neuroscience|||Proteases/Proteasome

• Bioactivity:

  AChE-IN-51 (compound 8C) is an orally active, non-competitive inhibitor of AChE and BChE, with IC50 values of 84 nM and 97 nM, respectively. It also inhibits MMP-2 and amyloid ? A?1-42 aggregation, with IC50 values of 724 nM and 302 nM. Exhibiting low cytotoxicity, AChE-IN-51 is predicted by computational models to penetrate the blood-brain barrier, making it a useful compound for research into diseases such as Alzheimer's disease (AD) .

• Molecular Formula:

  C23H21OP

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C