AChE-IN-51

CAT: 0931-T209001-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T209001-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

MMP, Beta Amyloid, Cholinesterase (ChE)

Related Pathways

Neuroscience, Proteases/Proteasome

Bioactivity

AChE-IN-51 (compound 8C) is an orally active, non-competitive inhibitor of AChE and BChE, with IC50 values of 84 nM and 97 nM, respectively. It also inhibits MMP-2 and amyloid β Aβ1-42 aggregation, with IC50 values of 724 nM and 302 nM. Exhibiting low cytotoxicity, AChE-IN-51 is predicted by computational models to penetrate the blood-brain barrier, making it a useful compound for research into diseases such as Alzheimer's disease (AD) .

Molecular Formula

C23H21OP

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
HY-157382	AChE-IN-51
304395-01	AChE (ACHE, Acetylcholinesterase)
A0526-20C	Acetylcholinesterase (ACHE, AChE)
122871	ACHE (Acetylcholinesterase, AChE)
220543-01	AChE (Acetylcholinesterase, AChE, ACHE, ACES) discontinued
122871-APC	ACHE (Acetylcholinesterase, AChE) (APC)
MBS6368542-01	ACHE (Acetylcholinesterase, AChE) (HRP)
MBS6368541-01	ACHE (Acetylcholinesterase, AChE) (FITC)
122871-Biotin	ACHE (Acetylcholinesterase, AChE) (Biotin)
304391	AChE (ACHE, Acetylcholinesterase, YT)

AChE-IN-51

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