AChE-IN-47

• Target:

  Cholinesterase (ChE)

• Related Pathways:

  Neuroscience

• Bioactivity:

  AChE-IN-47 (compound g17) is an acetylcholinesterase (AChE) inhibitor with an IC50 of 0.24 ?M. It prevents the self-aggregation of ?-amyloid peptides and exhibits neuroprotective properties by effectively reducing the accumulation of intracellular reactive oxygen species (ROS) .

• Smiles:

  O=C(NC=1C=CC=2C(=O)N3C(=NC2C1)CCC3)CNS(=O)(=O)C=4C=CC=CC4C(F)(F)F

• Molecular Formula:

  C20H17F3N4O4S

• Molecular Weight:

  466.43

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3033056-55-9