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Reveromycin C

CAT: 0931-T208698-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T208698-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
144860-69-5
Target
Antibacterial
Related Pathways
Microbiology/Virology
Bioactivity
Reveromycin C is a polyketide compound originally isolated from Streptomyces, exhibiting antifungal activity against Candida albicans with a MIC of 2.0 μg/mL at pH 3 and >500 μg/mL at pH 7.4. It inhibits EGF-induced mitogenic activity in Balb/MK mouse epidermal cell lines. Additionally, it reverses the morphology of sarcoma virus-transformed NRK rat kidney cells (EC50 = 1.58 μg/mL) and inhibits the proliferation of KB cells and K562 human chronic myelogenous leukemia cells (IC50 = 2.0 μg/mL for both) .
Smiles
O(C(CCC(O)=O)=O)[C@@]1(CCC(C)C)[C@H](/C=C/C(=C/C(O)=O)/C)O[C@@]2(CC1)O[C@H](C/C=C(/C=C/[C@@H]([C@H](/C=C/C(O)=O)C)O)\C)[C@@H](C)CC2
Molecular Formula
C37H54O11
Molecular Weight
674.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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