Reveromycin D

CAT: 0931-T37423Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T37423Size:1 mg
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CAS Number
144860-70-8
Target
Others|||Antibacterial
Related Pathways
Microbiology/Virology|||Others
Bioactivity
Reveromycin D is a bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells and exhibits pH-dependent antifungal activity against C. albicans [MICs = 2 and >500 ?g/ml at pH 3 and 7.4, respectively]. Reveromycin D also inhibits the proliferation of KB and K562 cells [IC50s = 1.6 and 1.3 ?g/ml, respectively].
Smiles
CCCCC[C@]1(CC[C@]2(CC[C@H](C)[C@@H](C\C=C(/C)\C=C\[C@H](O)[C@@H](C)\C=C\C(O)=O)O2)O[C@H]1\C=C\C(\C)=C\C(O)=O)OC(=O)CCC(O)=O
Molecular Formula
C37H54O11
Molecular Weight
674.82
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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R1988-03Reveromycin D
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