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PDE4B-IN-4

CAT: 0931-T207245-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207245-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PDE, TNF
Related Pathways
Apoptosis, Metabolism
Bioactivity
PDE4B-IN-4 is an inhibitor of PDE4B (IC50: 2.82 nM) and TNF-α (IC50: 7.20 nM) . It demonstrates anti-inflammatory properties by reducing neutrophilia in a mouse model of lipopolysaccharide (LPS) -induced sepsis.
Smiles
O=C1NC(N/N=C/C2=CC=C(OC)C(OC)=C2)=NC(C3=CC(OC4CCCC4)=C(OC)C=C3)=C1C#N
Molecular Formula
C26H27N5O5
Molecular Weight
489.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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