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Anticancer agent 273

CAT: 0931-T206951-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206951-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, Akt, PI3K
Related Pathways
PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Apoptosis
Bioactivity
Anticanceragent 273 (Compound 9q) is an effective anticancer compound identified from matrine. It inhibits cancer cell proliferation, with an IC50 of 4.48 μM against HeLa cells. Anticanceragent 273 exerts its anticancer effects by modulating PI3K/AKT expression and activating activating transcription factor 4 (ATF4), which induces endoplasmic reticulum stress and triggers apoptosis. It holds potential for cancer research, including cervical cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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