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HSTING activator-1

CAT: 0931-T206918-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206918-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
IFNAR, STING, Interleukin
Related Pathways
Immunology/Inflammation
Bioactivity
HSTING activator-1 (Compound 68) is a STING agonist capable of effectively activating various human STING variants (R232, H232, HAQ), with EC50 values of 56 nM, 89 nM, and 51 nM, respectively. This compound activates the type I interferon pathway by directly binding to the STING protein and stabilizing its conformation, which leads to downstream IRF3 phosphorylation and cytokine release. hSTING activator-1 also demonstrates potential in cancer research by inhibiting fibrosarcoma tumor growth.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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