AX-53802

CAT: 0931-MF-0063776-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0063776-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1008482-71-0
Target
Ferroptosis|||Glutathione Peroxidase
Related Pathways
Apoptosis|||Metabolism
Bioactivity
AX-53802 is a ferroptosis (ferroptosis) inducer targeting GPX4, with an IC50 of 0.34 µM. It forms a covalent bond with GPX4, initiating membrane translocation upon binding. In combination with FAK/Src inhibitors, AX-53802 enhances cell death. This compound is applicable in cancer research.
Smiles
O=C(C#C)N(C1=CC=C2OCOC2=C1)C(C(=O)NC3CCCC3)C=4C=CC=CC4F
Molecular Formula
C23H21FN2O4
Molecular Weight
408.422
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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