AX-53802

• Target:

  Ferroptosis|||Glutathione Peroxidase

• Related Pathways:

  Apoptosis|||Metabolism

• Bioactivity:

  AX-53802 is a ferroptosis (ferroptosis) inducer targeting GPX4, with an IC50 of 0.34 µM. It forms a covalent bond with GPX4, initiating membrane translocation upon binding. In combination with FAK/Src inhibitors, AX-53802 enhances cell death. This compound is applicable in cancer research.

• Smiles:

  O=C(C#C)N(C1=CC=C2OCOC2=C1)C(C(=O)NC3CCCC3)C=4C=CC=CC4F

• Molecular Formula:

  C23H21FN2O4

• Molecular Weight:

  408.422

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1008482-71-0