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HDAC6-IN-53

CAT: 0931-T206842-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206842-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
HDAC
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
HDAC6-IN-53 (Compound W28) is an inhibitor targeting histone deacetylase 6 (HDAC6) with an IC50 of 19.65 nM. It reduces the idiopathic pulmonary fibrosis (IPF) phenotype by inhibiting TGF-β1-induced collagen expression and demonstrates therapeutic efficacy in a bleomycin-induced mouse model of pulmonary fibrosis. HDAC6-IN-53 is applicable for research in idiopathic pulmonary fibrosis and related pulmonary fibrotic diseases.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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