Anticancer agent 271

• Target:

  MTOR|||EGFR|||PI3K

• Related Pathways:

  Tyrosine Kinase/Adaptors|||PI3K/Akt/mTOR signaling|||JAK/STAT signaling|||Angiogenesis

• Bioactivity:

  Anticanceragent 271 (compound 5C) exhibits antiproliferative activity against lung cancer (A549), colon cancer (Caco-2) cell lines, and human lung fibroblasts (WI38), with an IC50 value of 9.18 ?M for A549 cells. This compound can downregulate PI3K and mTOR gene expression and is applicable in cancer research.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C