MAT2A-IN-24

• Target:

  Methionine Adenosyltransferase (MAT)

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  MAT2A-IN-24 (Compound 9) is an inhibitor of methionine adenosyltransferase 2a (MAT2a), with an IC50 value of 20 nM for MAT2a inhibition and an antiproliferative IC50 value of 10 nM for HAP1MTAP–/– cells. MAT2A-IN-24 is applicable in the research of tumor diseases associated with MTAP deficiency.

• Smiles:

  O=C1N=C (C=2C=CC (Cl) =CC2N1C3=CC=CC (=C3) N4CCC (CN5C (=O) N=C (C=6C=CC (Cl) =CC65) N (C) C) CC4) N (C) C

• Molecular Formula:

  C32H33Cl2N7O2

• Molecular Weight:

  618.556

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3031093-57-6