MAT2A-IN-24

• Target :

  Methionine Adenosyltransferase (MAT)

• Related Pathways :

  Chromatin/Epigenetic

• Bioactivity :

  MAT2A-IN-24 (Compound 9) is an inhibitor of methionine adenosyltransferase 2a (MAT2a), with an IC50 value of 20 nM for MAT2a inhibition and an antiproliferative IC50 value of 10 nM for HAP1MTAP–/– cells. MAT2A-IN-24 is applicable in the research of tumor diseases associated with MTAP deficiency.

• Smiles :

  O=C1N=C(C=2C=CC(Cl)=CC2N1C3=CC=CC(=C3)N4CCC(CN5C(=O)N=C(C=6C=CC(Cl)=CC65)N(C)C)CC4)N(C)C

• Molecular Formula :

  C32H33Cl2N7O2

• Molecular Weight :

  618.556

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3031093-57-6