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SIK2/3-IN-1

CAT: 0931-T206638-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206638-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3038863-24-7
Target
SIK
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
SIK2/3-IN-1 (Compound 7S) is an orally active and selective inhibitor of SIK2/3. It significantly inhibits tumor growth without causing weight loss in the MV4-11 AML mouse CDX model. SIK2/3-IN-1 is applicable for research in MEF2C-dependent acute myeloid leukemia.
Smiles
O=C1C=2C(=NC(=CC2CCN1CC(F)(F)F)C=3C=C(C=NC3N)C=4C=NN(C4)C)OC
Molecular Formula
C20H19F3N6O2
Molecular Weight
432.399
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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