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SIK2/3-IN-2

CAT: 0013-GTR19274715-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274715-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SIK2/3-IN-2 (compound 12, compound I-200) is a potent SIK2/3 inhibitor, with IC50 values of 65 nM for SIK2 and 14 nM for SIK3. It also acts as an inhibitor of p21-activated kinase (PAK) 1, with a Ki of 20.7 nM. SIK2/3-IN-2 is applicable in research on proliferative diseases and cancer, such as paclitaxel-resistant ovarian cancer.
CAS Number
1648864-21-4
Smiles
C (N1C=2C (C=C (C1=O) C3=C (Cl) C=C (C=C3) C4=C (C) C=CC=N4) =CN=C (NC) N2) [C@H]5OC[C@H] (N) CO5
Molecular Formula
C25H25ClN6O3
Molecular Weight
492.96
Storage Conditions
-20°C
Notes
For research use only.

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