Products for Research Use Only

SHP2-IN-36

CAT: 0931-T206615-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206615-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Phosphatase
Related Pathways
Metabolism
Bioactivity
SHP2-IN-36 (Compound B8) is an allosteric inhibitor of SHP2 with an IC50 of 9.0 nM, and it exhibits an IC50 of 40 nM against p-ERK. Moreover, SHP2-IN-36 demonstrates significant antitumor activity in the KYSE520 xenograft mouse model and is applicable for research in the field of antitumor studies.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C