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(Rac) -Roscovitine

CAT: 0931-T206571-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206571-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
186692-44-4
Target
CDK, Apoptosis
Related Pathways
Cell Cycle/Checkpoint, Apoptosis
Bioactivity
(Rac) -Roscovitine ((Rac) -Seliciclib) is a selective inhibitor of cyclin-dependent kinases (CDKs) . It competes with ATP for binding at the active site of CDKs, thereby inhibiting their phosphorylation activity. This compound induces apoptosis in cancer cells and holds potential for the study of conditions like cancer, neurodegenerative diseases, heart diseases, viral and protozoal infections, glomerulonephritis, and chronic inflammation, all of which are associated with CDK dysregulation.
Smiles
OCC(NC=1N=C(NCC=2C=CC=CC2)C=3N=CN(C3N1)C(C)C)CC
Molecular Formula
C19H26N6O
Molecular Weight
354.449
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-50892-01(Rac) -Roscovitine
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