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RIP1-IN-1

CAT: 0931-T206258-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206258-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Necroptosis, RIP kinase
Related Pathways
NF-κB, Apoptosis
Bioactivity
RIP1-IN-1 is an orally bioavailable RIP1 inhibitor with a high binding affinity (Kd: 110 nM) . This compound exhibits significant activity against necroptosis and effectively suppresses necrosome formation by inhibiting the phosphorylation of RIP1, RIP3, and MLKL pathways. RIP1-IN-1 can inhibit necroptosis and is applicable in research on acute liver injury.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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