RIP1-IN-1

CAT: 0931-MF-0114322-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0114322-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Necroptosis|||RIP kinase
Related Pathways
NF-?B|||Apoptosis
Bioactivity
RIP1-IN-1 is an orally bioavailable RIP1 inhibitor with a high binding affinity (Kd: 110 nM) . This compound exhibits significant activity against necroptosis and effectively suppresses necrosome formation by inhibiting the phosphorylation of RIP1, RIP3, and MLKL pathways. RIP1-IN-1 can inhibit necroptosis and is applicable in research on acute liver injury.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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