RIP3 activator 1

• Target:

  Autophagy|||Necroptosis|||RIP kinase

• Related Pathways:

  NF-?B|||Autophagy|||Apoptosis

• Bioactivity:

  RIP3 Activator 1 (compound C8) is an effective RIP3 activator that inhibits cell growth and induces necroptotic cell death (necroptosis) and autophagy through the RIP3/p62/Keap1 signaling pathway. Additionally, this compound enhances the expression of p-MLKL and promotes the accumulation of LC3-II and p62 proteins.

• Smiles:

  C(OC[C@@H]1OC[C@H](N)[C@H]1O)C2=CN(CCCCCCCCCCCCCCCCCC)N=N2

• Molecular Formula:

  C26H50N4O3

• Molecular Weight:

  466.7

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1456899-52-7