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RIP3 activator 1

CAT: 0931-T201677-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201677-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1456899-52-7
Target
Autophagy, Necroptosis, RIP kinase
Related Pathways
NF-κB, Autophagy, Apoptosis
Bioactivity
RIP3 Activator 1 (compound C8) is an effective RIP3 activator that inhibits cell growth and induces necroptotic cell death (necroptosis) and autophagy through the RIP3/p62/Keap1 signaling pathway. Additionally, this compound enhances the expression of p-MLKL and promotes the accumulation of LC3-II and p62 proteins.
Smiles
C(OC[C@@H]1OC[C@H](N)[C@H]1O)C2=CN(CCCCCCCCCCCCCCCCCC)N=N2
Molecular Formula
C26H50N4O3
Molecular Weight
466.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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