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MS9024

CAT: 0931-T206183-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206183-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
DNA Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
MS9024 is a degrader of DNA methyltransferase 1 (DNMT1), facilitating its degradation in HCT116 cells via the ubiquitin-proteasome pathway, with a DC50 of 35 nM (DC50 values are 254 nM in MDA-MB-468 and 101 nM in H1299) . Additionally, MS9024 inhibits DNMT1 with an IC50 of 0.43 μM.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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