Products for Research Use Only

MS934

CAT: 0931-T79143-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79143-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2756323-15-4
Target
Raf, MEK, PROTACs
Related Pathways
MAPK, PROTAC
Bioactivity
MS934, a novel VHL-recruiting MEK 1/2 degrader, exhibits potent anti-proliferative effects on HT-29 cell growth, achieving a GI50 of 0.023 μM. It holds potential for researching various human cancers including melanoma, non-small cell lung cancer (NSCLC), colorectal cancer, primary brain tumors, and hepatocellular carcinoma [1].
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C([C@@H](NC(CCCCCCCCCCCNCCCCONC(=O)C1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1)=O)[C@](C)(C)C)(=O)N3[C@H](C(N[C@@H](C)C4=CC=C(C=C4)C5=C(C)N=CS5)=O)C[C@@H](O)C3
Molecular Formula
C52H69F3IN7O6S
Molecular Weight
1104.11
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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