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PROTAC c-Met degrader-3

CAT: 0931-T205572-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205572-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
C-Met/HGFR, PROTACs
Related Pathways
PROTAC, Tyrosine Kinase/Adaptors
Bioactivity
PROTACc-Met degrader-3 (Compound 22b) is a c-Met PROTAC degrader. It facilitates the ubiquitination and degradation of c-Met, with a DC50 of 0.59 nM in EBC-1 cells. PROTACc-Met degrader-3 is applicable in lung cancer research.
Smiles
COC1=C(C=C(C=C1)C(=O)N2CCC3(CCN(CC3)C(=O)CN4CCC(CC4)COC5=CN=C(N=C5)C6=CC=CC(=C6)CN7C(=O)C=CC(=N7)C8=CC=CC(=C8)C#N)CC2)N9CCC(=O)NC9=O
Molecular Formula
C51H54N10O7
Molecular Weight
919.037
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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