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PROTAC c-Met degrader-3

CAT: 0013-GTR19249209-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249209-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACc-Met degrader-3 (Compound 22b) is a potent, cell-permeable c-Met degrader with a DC50 of 0.59 nM in EBC-1 lung cancer cells. It facilitates targeted ubiquitination and proteasomal degradation of c-Met, making it a valuable chemical tool for investigating c-Met-dependent signaling in lung cancer research, both in vitro and in vivo.
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
COC1=C (C=C (C=C1) C (=O) N2CCC3 (CCN (CC3) C (=O) CN4CCC (CC4) COC5=CN=C (N=C5) C6=CC=CC (=C6) CN7C (=O) C=CC (=N7) C8=CC=CC (=C8) C#N) CC2) N9CCC (=O) NC9=O
Molecular Formula
C51H54N10O7
Molecular Weight
919.037
Storage Conditions
-20°C
Notes
For research use only.

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