ST-539

CAT: 0931-T205433-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T205433-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1040754-67-3
Target
DUB|||Autophagy
Related Pathways
Ubiquitination|||Autophagy|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Bioactivity
ST-539 is an inhibitor of the deubiquitinating enzyme USP30, with an IC50 of 0.37 ?M. It enhances the ubiquitination of mitochondrial proteins and induces mitophagy (autophagy), thereby regulating mitochondrial homeostasis. ST-539 is applicable for research in neurodegenerative diseases.
Smiles
O=C(NC(C(=O)NC1=CC=CC=2C1=CC=CC2S(=O)(=O)NC(C)(C)C)CC=3C=CC=CC3)C=4C=CC=CC4
Molecular Formula
C30H31N3O4S
Molecular Weight
529.65
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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