ST-539

• Target :

  DUB|||Autophagy

• Related Pathways :

  Ubiquitination|||Autophagy|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

• Bioactivity :

  ST-539 is an inhibitor of the deubiquitinating enzyme USP30, with an IC50 of 0.37 ?M. It enhances the ubiquitination of mitochondrial proteins and induces mitophagy (autophagy), thereby regulating mitochondrial homeostasis. ST-539 is applicable for research in neurodegenerative diseases.

• Smiles :

  O=C(NC(C(=O)NC1=CC=CC=2C1=CC=CC2S(=O)(=O)NC(C)(C)C)CC=3C=CC=CC3)C=4C=CC=CC4

• Molecular Formula :

  C30H31N3O4S

• Molecular Weight :

  529.65

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1040754-67-3