Anticancer agent 264

• Target :

  DNA/RNA Synthesis|||CDK

• Related Pathways :

  Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

• Bioactivity :

  Anticanceragent 264 (Compound 5w) is an anticancer compound that exhibits significant antiproliferative activity in tumor cell lines, with an IC50 range of 7.5-33.67 ?M. It notably induces cell cycle arrest at the G2/M phase in MDA-MB-231, MIA PaCa-2, and DU-145 cell lines. This compound reduces key cell cycle proteins CDK1, CDK2, and Cyclin B1 in a dose-dependent manner and has strong binding activity with differentiation inhibitors and DNA-binding proteins. Anticanceragent 264 is useful for research in the cancer disease domain.

• Molecular Formula :

  C23H18ClF5N6O

• Molecular Weight :

  524.87

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C