W23-1006

• Target:

  Apoptosis|||ALK

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors|||Apoptosis

• Bioactivity:

  W23-1006 is a selective covalent ALKBH5 inhibitor. It binds to the ALKBH5 C200 residue with an IC50 value of 3.848 ?M. The inhibitory activity of W23-1006 is approximately 30 times stronger than that of FTO and 8 times greater than that of ALKBH3. W23-1006 is applicable for research in triple-negative breast cancer (TNBC) .

• Smiles:

  O=C1NN(C(=O)C1=CC2=CC(Br)=CC(=C2)N(=O)=O)C3=CC=C(OC)C=C3

• Molecular Formula:

  C17H12BrN3O5

• Molecular Weight:

  418.198

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3035498-92-8