W23-1006

CAT: 0931-T205034-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T205034-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3035498-92-8
Target
Apoptosis|||ALK
Related Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors|||Apoptosis
Bioactivity
W23-1006 is a selective covalent ALKBH5 inhibitor. It binds to the ALKBH5 C200 residue with an IC50 value of 3.848 ?M. The inhibitory activity of W23-1006 is approximately 30 times stronger than that of FTO and 8 times greater than that of ALKBH3. W23-1006 is applicable for research in triple-negative breast cancer (TNBC) .
Smiles
O=C1NN(C(=O)C1=CC2=CC(Br)=CC(=C2)N(=O)=O)C3=CC=C(OC)C=C3
Molecular Formula
C17H12BrN3O5
Molecular Weight
418.198
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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