Autophagy inducer 6

CAT: 0931-MF-0113005-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0113005-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
ROS|||Apoptosis|||Reactive Oxygen Species|||COX|||Autophagy
Related Pathways
Immunology/Inflammation|||Apoptosis|||Neuroscience|||Autophagy|||Metabolism|||NF-?B
Bioactivity
Autophagyinducer 6 (Compound 3) inhibits the production of ROS and RNS by targeting COX-1 (IC50=15.3 µM) and COX-2 (IC50=4.58 µM) . It facilitates the formation of autophagosomes and induces autophagy (autopagy) as a cellular protection mechanism. Additionally, Autophagyinducer 6 triggers mild apoptosis (apoptosis) and suppresses the proliferation of cancer cell lines MC38, HCT116, and HCT29 with IC50 values of 9.5, 11.5, and 17.6 µM, respectively.
Molecular Formula
C10H19B9N2
Molecular Weight
264.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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