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Apoptosis inducer 35

CAT: 0931-T204472-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204472-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, p38 MAPK, Akt, ERK, EGFR
Related Pathways
Apoptosis, Tyrosine Kinase/Adaptors, MAPK, PI3K/Akt/mTOR signaling, JAK/STAT signaling, Angiogenesis, Cytoskeletal Signaling
Bioactivity
Apoptosisinducer 35 (Compound 6) is a multi-target inhibitor that reduces the expression of EGFR, AKT, ERK, and P38-MAPKα. It suppresses the proliferation of cancer cells A549 and Jurkat, induces cell cycle arrest at the S phase, and triggers apoptosis (cell death) .
Smiles
CCOC(=O)CSC1=NN=C(N1C2=CC=C(C=C2)Cl)CSC3=NN=C(N3N)C4=CC5=CC=CC=C5N4
Molecular Formula
C23H21ClN8O2S2
Molecular Weight
541.048
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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