Apoptosis inducer 35

• Target:

  Apoptosis|||p38 MAPK|||Akt|||ERK|||EGFR

• Related Pathways:

  Apoptosis|||Tyrosine Kinase/Adaptors|||MAPK|||PI3K/Akt/mTOR signaling|||JAK/STAT signaling|||Angiogenesis|||Cytoskeletal Signaling

• Bioactivity:

  Apoptosisinducer 35 (Compound 6) is a multi-target inhibitor that reduces the expression of EGFR, AKT, ERK, and P38-MAPK?. It suppresses the proliferation of cancer cells A549 and Jurkat, induces cell cycle arrest at the S phase, and triggers apoptosis (cell death) .

• Smiles:

  CCOC(=O)CSC1=NN=C(N1C2=CC=C(C=C2)Cl)CSC3=NN=C(N3N)C4=CC5=CC=CC=C5N4

• Molecular Formula:

  C23H21ClN8O2S2

• Molecular Weight:

  541.048

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C