FMP-API-1

• Target :

  PKA

• Related Pathways :

  Tyrosine Kinase/Adaptors

• Bioactivity :

  FMP-API-1 is an inhibitor of the A-kinase anchoring protein (AKAP) -PKA interaction. It binds to the allosteric site of the PKAR subunit, enhancing the activity of PKA and AQP2 in PKA knockout cell lines of the renal cortex collecting duct (mpkCCD cells) . FMP-API-1 holds potential for studying nephrogenic diabetes insipidus (NDI) .

• Smiles :

  OC1=CC=C(C=C1N)CC2=CC=C(O)C(N)=C2

• Molecular Formula :

  C13H14N2O2

• Molecular Weight :

  230.262

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  16523-28-7